What We Can Learn from Twins: Congenital Heart Disease in the Danish Twin Registry Running title: Mahle; Congenital heart disease in twins
نویسنده
چکیده
Children's H H Hea ea ealt lt lthc hc hcar ar are e e of of o A A Atl tl tla an a ta ta ta
منابع مشابه
What we can learn from twins: congenital heart disease in the danish twin registry.
O ur understanding of the causes of congenital heart defects has benefited tremendously from state-of-the-art genetic and epigenetic tools. The rapid progress is due in part to the development of novel, high-throughput, cost-effective sequencing technology—so-called next-generation sequenc-ing—that has made it possible to sequence the entire genome or all genes (whole exome sequencing). However...
متن کاملIncreased prevalence of congenital heart defects in monozygotic and dizygotic twins.
BACKGROUND Smaller studies and many case series reports indicate that congenital heart defects may be more common in monochorionic twins than in dichorionic twins and singletons. METHODS AND RESULTS We investigated congenital heart defect occurrence in all twins and 5% of all singletons born in Denmark in 1977-2001 and followed through 2006 by linking the Danish Twin Registry and Statistics D...
متن کاملInfluence of twin-twin transfusion syndrome on fetal cardiovascular structure and function: prospective case-control study of 136 monochorionic twin pregnancies.
OBJECTIVE To test the hypothesis that identical twins show no inter-twin differences in cardiovascular structure or physiology in fetal life unless there has been twin-twin transfusion syndrome. DESIGN Unselected prospective case-control observational study of fetoplacental haemodynamics including echocardiography at a median of 24 (16.7 to 32.3) weeks, with postnatal confirmation of congenit...
متن کاملAuricular septal defect in one of monozygotic twins.
In the cardiac clinic of the Hospital for Sick Children, Toronto, a 6-year-old girl with an auricular septal defect was found to have a monozygotic twin in whom the heart was normal. Instances of congenital heart disease in both of monozygotic twins have been reported by several authors. Smith (1929) observed a patent ductus arteriosus in both of twin boys of similar general appearance, size, a...
متن کاملThe Importance of Examining Congenital Hypothyroidism in Connection with Congenital Heart Disease: Letter to Editor
Dear Editor-in-Chief: I read and enjoyed your stylish article, "Frequency of Congenital Cardiac Malformations in Neonates with Congenital Hypothyroidism", in relation to heart disease with hypothyroidism. As we know, one of the most commonly associated congenital hypothyroidism disorders is congenital heart disease, which has a significant effect on the recovery of pat...
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